Cardiac grafts pteridine cyclosporinA and NIL treated. Mus musculus

NIAID Data Ecosystem2026-03-06 收录

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药物干预机制

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA90291 数据链接链接失效反馈

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Tetrahydrobiopterin compounds prolong allograft survival independent of their effect on nitric oxide synthase activity Keywords: other

创建时间：

2005-02-28

Tacrolimus- and sirolimus-induced human b cell dysfunction is reversible and preventable

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毒液转录组学

We used RNA-seq to investigate transcriptional changes in human islet grafts that were treated in vivo with tacrolimus or sirolimus. We show that this treatment induces broad transcriptional dysregula

NIAID Data Ecosystem110

Data_Sheet_1_Human Recombinant Alkaline Phosphatase (Ilofotase Alfa) Protects Against Kidney Ischemia-Reperfusion Injury in Mice and Rats Through Adenosine Receptors.PDF

缺血再灌注损伤

药物干预机制

Adenosine triphosphate (ATP) released from injured or dying cells is a potent pro-inflammatory “danger” signal. Alkaline phosphatase (AP), an endogenous enzyme that de-phosphorylates extracellular ATP

NIAID Data Ecosystem40

Data Sheet 1_Interaction between HLA-B leader peptide variants and cytomegalovirus serostatus is associated with early T cell-mediated rejection in kidney transplantation.pdf

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HLA遗传变异与排斥反应

Mismatches between mature recipient and donor HLA proteins can trigger alloreactivity upon transplantation. Recent studies suggest that also the leader peptide of HLA class I alleles may affect the tr

NIAID Data Ecosystem20

T Cell Expression of AhR Inhibits the Maintenance of pTreg Cells in the GI Tract in Acute GvHD. Mus musculus

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细胞转录组分析

Transcriptome analysis of murine T cells pre- and post-transplant. Overall design: Sorted CD4 and CD8 splenic T cells where evaluated by RNA-seq either at the time of allogeneic transplant or 14 days

NIAID Data Ecosystem80

Eosinophils in Lung Allograft

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嗜酸性粒细胞炎症

Eosinophils were isolated from the lungs of mice that were resting naÃ¯ve or 7 or 30 days post-transplant with costimulatory blockade Overall design: Lungs of 3 to 5 mice were pooled per sample. Lung

NIAID Data Ecosystem40

Cardiac grafts pteridine cyclosporinA and NIL treated. Mus musculus

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