Diagnostic findings of cryptococcosis disease (N = 207) stratified by disease severity at initial presentation and underlying condition.

aSevere disease: HIV group had 74 patients, transplant group had 18 patients and 39 patients were in the HIV-negative/non-transplant group; Non-severe disease: HIV group had 12 patients, transplant group had 24 patients and 40 patients were in the HIV-negative/non-transplant group.bLumbar puncture; 176 total patients had an LP. Six HIV-negative, non-transplant patients with severe disease did not receive an LP and the remaining 25 patients without an LP were non-severe cases (18 HIV-negative/non-transplant, six transplant recipients, and one HIV-positive patient). Percentages relevant to the LP procedure reflect missing observations.cSignificantly associated with attributable-mortality.dEleven (15%) HIV-infected patients had missing documentation of CSF host (nucleated) cells (overall N = 63); excluding the six with no initial LP, five HIV-negative, non-transplant were missing host cell counts (overall N = 28).eOpening pressure; maximum LP OP was used for this variable, as initial LP OP was infrequently captured. Denominators for each group with severe disease were 74, 8, and 33, respectively.