Only a matter of time (OMIT) Study - A comparison of caloric restriction versus time restriction of food intake

This is a dataset of 114 participants (adults aged 35-75 years old) who are overweight or obese (BMI 25.1 - 44.9 kg/m2), have elevated waist circumference (race specific) and elevated fasting blood glucose (>5.6 mmol/L). This study compares caloric restriction (CR) diets that restrict the amount of food that is eaten with CR diets that also restrict the time that the food is eaten, to either early or late in the day, on risk factors for type 2 diabetes and cardiovascular diseases over 8 weeks.
The primary outcome is the change in glucose area under curve (AUC) after 3 meals at baseline and at 8 weeks. Secondary end points include insulin area AUC, fasting insulin and glucose, and change in glycated hemoglobin (HbA1c) at baseline and at 8 weeks.