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Investigation of bile acid signaling and liver size in a mouse model wherein the mouse liver is repopulated with human liver cells
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创建时间:
2017-11-21
相关数据集
Bile Acid Flux Is Necessary for Normal Liver Regeneration
Background & Aims Many signals governing liver regeneration (LR) following 2/3 partial hepatectomy (PH) are recognized, but the primary signal(s) remains unknown. The aim of the study was to confirm t
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FGF19-FGFR4 promotes the progression of gallbladder carcinoma in a biliary autocrine pathway dependent on GPBAR1-EGR1 axis. FGF19-FGFR4 promotes the progression of gallbladder carcinoma in a biliary autocrine pathway dependent on GPBAR1-EGR1 axis
GBC is the most common type of biliary tract cancers and the seventh most common gastrointestinal cancer. Most patients are diagnosed as GBC in an unresectable stage because of the silent symptoms. Ev
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Bile acid flux is necessary for normal liver regeneration
Bile acid return from the intestine and attendant signaling is necessary for liver regeneration after partial hepatectomy or CCl4 injury Overall design: Three groups of rat liver were examined at 4 ti
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DCA-TGR5 signaling activation alleviates inflammatory response and improves cardiac function in myocardial infarction
The progression of myocardial infarction (MI) involves multiple metabolic disorders. Bile acid metabolites have been increasingly recognized as pleiotropic signalling molecules that regulate multiple
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A Farnesoid X Receptor-Bile Acid Axis Contribute to Immune Evasion in Intestinal Gastric Cancer
Gastric cancer (GC) is the fifth most common type of cancer and the third leading cause of cancer-associated mortality worldwide. The tumor microenvironment (TME) is a complex system composed of extra
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