首页/数据集/Epigenetic therapy activates TE-chimeric transcripts to provide additional source of antigens in glioblastoma stem cells

Epigenetic therapy activates TE-chimeric transcripts to provide additional source of antigens in glioblastoma stem cells

NIAID Data Ecosystem2026-05-02 收录

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表观遗传抗原激活

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP426514 数据链接链接失效反馈

官方服务：

资源简介：

Epigenetic treatment induces TE-chimeric antigens in glioblastoma stem cells Overall design: Methylation profiling by high throughput sequencing

应用场景：

创建时间：

2024-09-05

CAR-T细胞优化

胶质母细胞瘤免疫治疗

Glioblastoma (GBM) is the most prevalent primary malignant brain tumor, containing self-renewing stem-like GBM stem cells (GSCs) that have been a focus of immunotherapies. Chimeric antigen receptor (C

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Additional file 7 of Epigenetic remodeling to improve the efficacy of immunotherapy in human glioblastoma: pre-clinical evidence for development of new immunotherapy approaches

胶质母细胞瘤免疫治疗

表观遗传药物机制

Additional file 7: Table S1: Upstream regulators by guadecitabine in all tumor types; Table S2: Enrichment analysis of Upstream regulators up-regulated in GBM vs MM-BM; Table S3: Enrichment analysis o

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Losartan controls immune checkpoint blocker-induced edema and improves survival in glioblastoma

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Immune checkpoint blockers (ICBs) have failed in all Phase III glioblastoma trials. Here, we found that ICBs induce cerebral edema in some patients and mice with glioblastoma. Through single-cell RNA

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Supplementary Table 8 from Quantitative Cell Type–Specific Immunopeptidome Analysis of Macrophage and Tumor Coevolution Reveals Therapeutic MHC-I Peptides in Glioblastoma

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胶质母细胞瘤免疫治疗

Peptide quantification in TMT labeled anti-flammatory macrophages and naïve macrophage

Figshare2025-12-15 更新50