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RNA-sequencing of in vitro differentiated WT and Chi3l1 KO Th1 cell

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NIAID Data Ecosystem2026-03-12 收录
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We report the differential mRNA expressino of WT and Chi3l1 KO Th1 cells. We cultured WT and Chi3l1 KO naive CD4 T cells under Th1 skewing condition : plate-bound anti-CD3/28 antibody (2ug/mL), IL-12 0.2ng/mL, IL-2 50U/mL, anti-IL-4 neutralizing antibody 2ug/mL, for 3 days. We found different Th1 regulatory and tumoricidal-related gene expression in Chi3l1 KO T cells. Comparison of RNA expressino in WT and Chi3l1 KO Th1 cells

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2021-07-25
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