Ipilimumab-induced reactions of the respiratory tract and renal system.

*case is detailed in the result section.
alisted treatments are systemic treatments unless otherwise specified.
btumor-free high-risk stage III melanoma (AJCC 2009); adjuvant administration of ipilimumab.
cstage IV metastatic disease (AJCC 2009).
dPRAME study; vaccination with GSK2302025A.
eatypical pneumonia.
facute renal failure.
grenal failure/atypical pneumonia.
hiridocyclitis/keratitis, deafness.
Irenal failure/atypical pneumonia/iridocyclitis/keratitis.
jdeafness.
M indicates male; F, female; LN, lymph nodes; IFN-α, interferon-α; DTIC, dacarbazine; DVP; polychemotherapy with dacarbazine/vindesine/paclitaxel; GIT, gastrointestinal tract; PR, partial response; SD, stable disease; MR, mixed response; PD, progressive disease.