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MethylationEPIC - Epigenetic Activation of AKT1 Drives Metabolic Reprogramming in Advanced-Stage Lipedema: A Multi-Omics Study

ChEBI2025-08-12 更新2026-07-12 收录

脂肪水肿病理机制

表观遗传重编程

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-15365 数据链接链接失效反馈

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MethylationEPIC - Epigenetic Activation of AKT1 Drives Metabolic Reprogramming in Advanced-Stage Lipedema: A Multi-Omics Study

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创建时间：

2025-08-12

训练免疫

表观遗传重编程

Trained immunity is a long-term memory of innate immune cells, generating an improved response upon re-infection. Shigella is an important human pathogen and inflammatory paradigm for which there is n

NIAID Data Ecosystem90

Active and Passive Demethylation of Male and Female Pronuclear DNA in the Mammalian Zygote

受精卵DNA去甲基化

表观遗传重编程

The epigenomes of mammalian sperm and oocytes, characterized by gamete-specific 5-methylcytosine (5mC) patterns, are reprogrammed during early embryogenesis to establish full developmental potential.

NIAID Data Ecosystem50

HIF-1 directly induces TET3 expression to redistribute 5-hydroxymethylcytosine and induce erythroid gene expression in hypoxia [RNA-seq]. HIF-1 directly induces TET3 expression to redistribute 5-hydroxymethylcytosine and induce erythroid gene expression in hypoxia [RNA-seq]

红细胞生成低氧应答

表观遗传重编程

We performed RNA-sequencing on erythropoietic cells cultured in normoxia or hypoxia at days 3,7, and 10. We found numerous expression changes induced by hypoxia, including the canonical hypoxia target

NIAID Data Ecosystem40

Ago1 controls myogenic differentiation by regulating eRNA mediated CBP guided epigenome reprogramming

肌肉分化调控

表观遗传重编程

The role of Argonaute (Ago) proteins in post-transcriptional gene silencing in the cytoplasm is well characterized. However, its nuclear function still remains elusive. In this work, we investigated t

NIAID Data Ecosystem50

Selective reactivation of human X-linked genes in female fibroblasts reprogrammed by cell fusion. Selective reactivation of human X-linked genes in female fibroblasts reprogrammed by cell fusion

X染色体再激活

表观遗传重编程

In female mammals, one of the two X chromosomes is silenced as pluripotent cells differentiate. This process, termed X-inactivation, is random and results in mosaic expression of many X-linked genes i

NIAID Data Ecosystem40

MethylationEPIC - Epigenetic Activation of AKT1 Drives Metabolic Reprogramming in Advanced-Stage Lipedema: A Multi-Omics Study

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