Per allele hazard ratios (HR) and 95% confidence intervals (CI) of previously published breast cancer loci among BRCA2 mutation carriers from previous reports and from the iCOGS array, ordered by statistical significance of the region.
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1Reporting status of the SNP is either previously reported or novel to this report.2p-value was calculated based on the 1-degree of freedom score test statistic.3rs311499 could not be designed onto the iCOGS array. A surrogate (r2 = 1.0), rs311498, was included, however, and reported here.4Stronger associations were originally reported for the SNP, assuming a dominant or recessive model of the ‘risk allele’.
创建时间:
2015-12-02



