Structure of HIV PR resistant patient derived mutant (comprising 22 mutations) in complex with DRV
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Structure of HIV PR resistant patient derived mutant (comprising 22 mutations) in complex with DRV Descriptor: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, BETA-MERCAPTOETHANOL, HIV-1 protease, ... Authors: Rezacova, P, Kozisek, M, Konvalinka, J, Saskova, K.G. Deposit date: 2011-07-25 Release date: 2012-06-20 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Mutations in HIV-1 gag and pol Compensate for the Loss of Viral Fitness Caused by a Highly Mutated Protease. Antimicrob.Agents Chemother., 56, 2012
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2011-07-25
