Effect of Helicobacter pylori on ATM-dependent DNA damage responses [cell lines]

ChEBI2014-08-23 更新2026-07-21 收录

幽门螺杆菌致病机制

DNA损伤应答

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-60661 数据链接链接失效反馈

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Effect of Helicobacter pylori on ATM-dependent DNA damage responses [cell lines]

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2014-08-23

Gastric Tissue Proteomics in H. pylori WT- and H. pylori GGT-knockout-Treated Mice

幽门螺杆菌致病机制

瘤胃蛋白质组学

Gamma-glutamyltransferase (GGT), an important virulence factor of Helicobacter pylori (Hp), is known to cause glutathione depletion in host cells. Here, this study finds that HpGGT promotes epithelial

科学数据银行2025-04-10 更新40

Phosphorylation of murine p53 at Ser-18 regulates the p53 responses to DNA damage

磷酸化调控

DNA损伤应答

Ser-15 of human p53 (corresponding to Ser-18 of mouse p53) is phosphorylated by ataxia-telangiectasia mutated (ATM) family kinases in response to ionizing radiation (IR) and UV light. To determine the

PubMed Central2000-10-17 更新30

ATM INDUCES MACROD2 NUCLEAR EXPORT UPON DNA DAMAGE

DNA损伤应答

ATM信号转导

ADP-ribosylation is a dynamic post-translation modification that regulates the early phase of various DNA repair pathways by recruiting repair factors to chromatin. ADP-ribosylation levels are defined

NIAID Data Ecosystem20

Neurons burdened by DNA double strand breaks incite microglia activation through antiviral-like signaling in neurodegeneration.

炎症机制

DNA损伤应答

DNA double strand breaks (DSBs) are linked to neurodegeneration and senescence. However, it is not clear how DSB-bearing neurons influence neuroinflammation associated with neurodegeneration. Here, we

NIAID Data Ecosystem30

Supplementary Table S4 from Ataxia Telangiectasia-Mutated–Dependent DNA Damage Checkpoint Functions Regulate Gene Expression in Human Fibroblasts

DNA损伤应答

基因表达调控

Supplementary Table S4 from Ataxia Telangiectasia-Mutated–Dependent DNA Damage Checkpoint Functions Regulate Gene Expression in Human Fibroblasts

Figshare2007-08-01 更新20