Impact of Chronic Rhinosinusitis on Severe Asthma Patients

The data expressed as mean ± standard error of mean (SEM). Statistical significance for intergroup  comparisons  was  determined  by  Mann-Whitney  U  test  for  continuous  variables  and Fisher’s exact test for categorical variables. The correlations between demographic data, clinical laboratory tests, expression of cytokines in nasal tissue, as well as clinical symptom scores, endoscopy scores, CT scores, pulmonary function tests, ACT scores, cytokine levels, and  ILC2  cell  counts  were  determined  using  the  Spearman's  coefficient.  All  statistical analysis was performed using the GraphPad Prism (version 5) software package (GraphPad  Prism Software, Inc, San Diego, CA). P value less than 0.05 is significant.