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Fofie, Granja-Vazquez, Truong, Walsh, Price, Biswas, Dussor, Pancrazio, Kolber. (2025) Profiling Human iPSC-Derived Sensory Neurons for Analgesic Drug Screening Using a Multi-Electrode Array. <i>Cell Reports Methods </i>2025 Raw data.xlsx

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These raw data are from a published manuscript - Fofie, Granja-Vazquez, Truong, Walsh, Price, Biswas, Dussor, Pancrazio, Kolber. (2025) Profiling Human iPSC-Derived Sensory Neurons for Analgesic Drug Screening Using a Multi-Electrode Array. Cell Reports Methods Fofie et al. present a high-content screening platform using hiPSC-derived nociceptors cultured on multi-well multi-electrode arrays to identify peripheral analgesics with diverse mechanisms of action. This scalable system shows robust activity, pharmacological relevance, and transcriptomic validation, enabling the discovery of 39 potential hits from a 704-compound natural product library.

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2025-04-19
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