Transcritomic analysis of PHF8 mediated genes in MKN28, human gastric cancer cells
收藏NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE117980
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资源简介：
PHF8, an important epigenetic regulator of cell cycle progression, rRNA synthesis and chromatin organization, is often overexpressed in different types of cancer including gastric cancer. Notably, elevated expression of PHF8 is associated with a poor clinical outcome in patients with gastric cancer. A global transcriptomic analysis between control and PHF8-knockdown MKN28 cells reveals differentially expressed genes involved in cell mortility and cell migration, suggesting PHF8 acts as an important regulator of cell migration related genes. PHF8 control and knockdown cell lines were established in MKN28 cells via a lentiviral-based system: LKO (control) and shPHF8 ( PHF8 targeted shRNA )
创建时间：
2020-09-26
