Discovery of Novel Potent and Selective Agonists at the Melanocortin‑3 Receptor
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https://figshare.com/articles/dataset/Discovery_of_Novel_Potent_and_Selective_Agonists_at_the_Melanocortin_3_Receptor/2094670
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资源简介：
The
melanocortin receptors 3 and 4 control energy homeostasis, food-intake
behavior, and correlated pathophysiological conditions. The melanocortin-4
receptor (MC4R) has been broadly investigated. In contrast, the knowledge
related to physiological roles of the melanocortin-3 receptor (MC3R)
is lacking because of the limited number of known MC3R selective ligands.
Here, we report the design, synthesis, biological activity, conformational
analysis, and docking with receptors of two potent and selective agonists
at the human MC3 receptor.
创建时间：
2016-02-12
