Metabolism under the control of Per2.

Shown are the top metabolic genes accounting for the identification of carbohydrate or fatty acid metabolism as top networks or canonical pathways when analyzing genes that are only regulated in wildtype but not in Per2−/− mice using different ischemia and reperfusion protocols. WT = wildtype, I30 = 30 minutes of ischemia, IP0 = ischemic preconditioning (4 times 5 minutes of ischemia and reperfusion), I30R60 = 30 minutes of ischemia and 60 minutes of reperfusion. Given are the expression values (fold change) obtained by Ingenuity pathway analysis. Bold genes appear in more than one treatment group, indicating a robust differentially regulated gene.