Carboxylesterases (CEs) are ubiquitous enzymes that are responsible for the metabolism of xenobiotics, including drugs such as irinotecan and oseltamivir. Inhibition of CEs significantly modulates the
The weighted kappa coefficient of a binary diagnostic test (BDT) is a measure of performance of a BDT, and is a function of the sensitivity and the specificity of the diagnostic test, of the disease p