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Diheteromeric GluN1/GluN2A (delM653) in nanodisc complexed with glycine, glutamate, and GNE-4123, open conformation

NIAID Data Ecosystem2026-05-10 收录

NMDA受体结构解析

神经受体配体

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Diheteromeric GluN1/GluN2A (delM653) in nanodisc complexed with glycine, glutamate, and GNE-4123, open conformation

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创建时间：

2026-02-04

NMDA受体

神经受体配体

GluN2D ligand-binding core in complex with propyl-NHP5G Descriptor: (2R)-amino(1-hydroxy-4-propyl-1H-pyrazol-5-yl)ethanoic acid, Glutamate receptor ionotropic, NMDA 2D Authors: Hansen, K.B, Tajima, N,

Protein Data Bank Japan2024-10-30 更新100

BindingDB Entry 50018147: Structure-activity relationships of mixed σ

神经受体配体

分子药理学

Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, ATP-dependent translocase ABCB1, D(2) dopamine receptor, Muscarinic acetylcholine receptor M1, Muscarinic acetylcholine recepto

DataCite Commons2024-04-26 更新30

Structure of the human GluN1/GluN2A LBD in complex with compound 9 (GNE3500)

NMDA受体结构解析

正变构调节剂设计

Structure of the human GluN1/GluN2A LBD in complex with compound 9 (GNE3500) Descriptor: (1R,2R)-2-(2-{[5-chloro-3-(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-7-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-6-

Protein Data Bank Japan2024-10-09 更新20

Structure of GluN1a E698C-GluN2D NMDA receptor in cystines crosslinked state.

NMDA受体结构解析

神经受体门控机制

Structure of GluN1a E698C-GluN2D NMDA receptor in cystines crosslinked state. Descriptor: Glutamate receptor ionotropic, NMDA 1, NMDA 2D Authors: Zhang, J.L, Zhu, S.J, Zhang, M. Deposit date: 2022-07-

Protein Data Bank Japan2024-11-20 更新50

GluA2flip sLBD complexed with FW and (R,R)-2b crystal form F

AMPA受体

神经受体配体

GluA2flip sLBD complexed with FW and (R,R)-2b crystal form F Descriptor: 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, Glutamate receptor 2,Glutamate receptor 2, N,N'-[b

Protein Data Bank Japan2024-10-09 更新20

Diheteromeric GluN1/GluN2A (delM653) in nanodisc complexed with glycine, glutamate, and GNE-4123, open conformation

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