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The choroidal nervous system: A link between corticoids and chorioretinopathy

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP439642
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Transgenic mice overexpressing human mineralocorticoid receptor (hMR) under the control of the ecologic promotor 1 (P1 hMR mice) were used as well as their WT littermates. We observed anatomical signs of choroid neuropathy in these mice. Bulk-transcriptomic analysis of retinal pigment epithelium/choroid complex was peformed to identify potential mechanisms. Overall design: Animals were sacrified and eyes were freshly dissected to extract RNA from RPE/choroid complex for transcriptomic analysis.
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2024-04-29
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