COGNANO/AVIDa-SARS-CoV-2

---
license: cc-by-nc-4.0
tags:
- biology
- protein
- antibody
- VHH
---

## AVIDa-SARS-CoV-2

AVIDa-SARS-CoV-2 is a dataset featuring the antigen-variable domain of heavy chain of heavy chain antibody (VHH) interactions obtained from two alpacas immunized with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike proteins.
AVIDa-SARS-CoV-2 includes binary labels indicating the binding or non-binding of diverse VHH sequences to 12 SARS-CoV-2 mutants, such as the Delta and Omicron variants.
Further details on AVIDa-SARS-CoV-2 are described in our paper "[A SARS-CoV-2 Interaction Dataset and VHH Sequence Corpus for Antibody Language Models](https://arxiv.org/abs/2405.18749).”

## Columns

**AVIDa-SARS-CoV-2.csv / train.csv / test.csv**

| Column | Description |
| --------------- | --------------------------------------------------------------------------------- |
| VHH_sequence | Amino acid sequence of VHH |
| Ag_label | Antigen Type |
| label | Binary label represented by 1 for the binding pair and 0 for the non-binding pair |
| subject_species | Species of the subject from which VHH was collected |
| subject_name | Name of the subject from which VHH was collected |
| subject_sex | Sex of the subject from which VHH was collected |

**antigen_sequences.csv**

| Column | Description |
| ----------- | ------------------------------ |
| Ag_label | Antigen Type |
| Ag_sequence | Amino acid sequence of antigen |

## Links

- Project Page: https://avida-sars-cov-2.cognanous.com
- Code: https://github.com/cognano/AVIDa-SARS-CoV-2
- Paper: https://arxiv.org/abs/2405.18749

## Citation

If you use AVIDa-SARS-CoV-2 in your research, please cite the following paper.

```bibtex
@inproceedings{tsuruta2024sars,
title={A {SARS}-{C}o{V}-2 Interaction Dataset and {VHH} Sequence Corpus for Antibody Language Models},
author={Hirofumi Tsuruta and Hiroyuki Yamazaki and Ryota Maeda and Ryotaro Tamura and Akihiro Imura},
booktitle={Advances in Neural Information Processing Systems 37},
year={2024}
}
```

原始信息汇总

数据集概述

数据集名称

• AVIDa-SARS-CoV-2

数据集描述

• AVIDa-SARS-CoV-2 是一个包含来自两只免疫于严重急性呼吸综合征冠状病毒2（SARS-CoV-2）刺突蛋白的羊驼的抗原-可变域重链抗体（VHH）相互作用的数据集。该数据集包含多样VHH序列与12种SARS-CoV-2变种（如Delta和Omicron）的结合或非结合的二元标签。

数据集内容

• 主要文件：
  • AVIDa-SARS-CoV-2.csv / train.csv / test.csv
    • VHH_sequence：VHH的氨基酸序列
    • Ag_label：抗原类型
    • label：二元标签，1表示结合，0表示非结合
    • subject_species：VHH来源的物种
    • subject_name：VHH来源的个体名称
    • subject_sex：VHH来源的个体性别
  • antigen_sequences.csv
    • Ag_label：抗原类型
    • Ag_sequence：抗原的氨基酸序列

数据集许可证

• 许可证：cc-by-nc-4.0

数据集标签

• 标签：biology, protein, antibody, VHH

引用信息

• 引用文献： bibtex @article{tsuruta2024sars, title={A {SARS}-{C}o{V}-2 Interaction Dataset and {VHH} Sequence Corpus for Antibody Language Models}, author={Hirofumi Tsuruta and Hiroyuki Yamazaki and Ryota Maeda and Ryotaro Tamura and Akihiro Imura}, journal={arXiv preprint arXiv:2405.18749}, year={2024} }