Changes in relative concentrations of key metabolites in lamb plasma during postnatal developmenta.

aData were obtained by using relative intensities of plasma metabolites in 73 samples, comprising 36 (14 NmatCpat+22 NmatNpat) and 37 (16 NmatCpat+21 NmatNpat) plasma samples collected at 8 and 12 weeks of age, respectively. Concentrations of metabolites identified in Table S1, but not listed in this table, did not change significantly.bVIP, Variable Importance in the Projection. Variables with VIP >1 were considered significant [52].cFold changes of metabolites in plasma at 12 weeks compared with 8 weeks of age.dLabeled P values were obtained from Mann–Whitney U test and other P values were determined by Student’s t test.eBH Padj, significance levels of metabolites after Benjamini-Hochberg multiple testing correction.f,gMean ± one standard deviation, n = 36 and 37, respectively.hTMAO, trimethylamine N-oxide.iUnidentified metabolites.