Hypertension affects one-third of the world's population, leading to cardiac dysfunction that is modulated by resident and recruited immune cells. Cardiomyocyte growth is essential to withstand hypert

NIAID Data Ecosystem60

Arabidopsis requires a stearoyl-ACP desaturase for proper interaction with beneficial rhizobacteria

微生物互作

代谢免疫调控

Unlike pathogens that trigger plant defense responses, beneficial microbes are compatible with plants. One possible reason for the compatibility is that the microbial factors from beneficial microbes

NIAID Data Ecosystem50

DataSheet1_α-Mangostin Alleviated Inflammation in Rats With Adjuvant-Induced Arthritis by Disrupting Adipocytes-Mediated Metabolism-Immune Feedback.PDF

抗炎药物机制

代谢免疫调控

A previously identified anti-rheumatic compound α-mangostin (MAN) possesses notable metabolism regulatory properties. In this study, we investigated the immune implication of MAN-altered fat metabolis

NIAID Data Ecosystem70

DataSheet_1_Extracellular Lactate Acts as a Metabolic Checkpoint and Shapes Monocyte Function Time Dependently.pdf

代谢免疫调控

单核细胞炎症应答

Elevated blood lactate levels are frequently found in critically ill patients and thought to result from tissue hypoperfusion and cellular oxygen shortage. Considering the close relationship between i

NIAID Data Ecosystem60

Integrated metabolic modelling reveals cell-type specific epigenetic control points of the macrophage metabolic network

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