LDSPEC_data_release_120223

Data release accompanying initial submission (120223) of the paper "Pervasive correlations between causal disease
effects of proximal SNPs vary with functional annotations and implicate stabilizing selection".
snp_info.zip: .pvar file of 14,820,648 imputed SNPs. "snp_list_chr@.MAF_001_INFO_06.txt" contains the list of MAF>0.1% and INFO>0.6 SNPs. "ukb_imp_chr@_v3_aa.pvar" contains the final set of SNPs where "REF_Chimp" was used as the ancestral allele (opposite of derived allele)annot_single165.zip: 165 single-SNP annotations in the baseline-SP model (across 14,820,648 imputed SNPs).annot_pair136.zip: 136 SNP-pair annotations in the baseline-SP model (across 14,820,648 imputed SNPs).main.avgr: LDSPEC ".avgr" file for average LD (r) of the SNP-pair annotations.trait_list_paper.txt: list of 70 diseases/traits analyzed in the paper.ldspec_results.zip: LDSPEC results for 70 diseases/traitsAdditionally, other data files are in separate folders:
LD scores and directional LD scores: https://figshare.com/account/projects/188052/articles/24716901GWAS summary statistics: https://figshare.com/account/projects/188052/articles/24716952