Double-stranded RNA induces molecular and inflammatory signatures that are directly relevant to COPD

ChEBI2013-02-27 更新2026-07-21 收录

慢性阻塞性肺病机制

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-39304 数据链接链接失效反馈

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Double-stranded RNA induces molecular and inflammatory signatures that are directly relevant to COPD

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2013-02-27

Probenecid Blocks Human P2X7 Receptor-Induced Dye Uptake via a Pannexin-1 Independent Mechanism

P2X7受体

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P2X7 is a ligand-gated ion channel which is activated by ATP and displays secondary permeability characteristics. The mechanism of development of the secondary permeability pathway is currently unclea

NIAID Data Ecosystem70

Activation of GPR4 by Acidosis Increases Endothelial Cell Adhesion through the cAMP/Epac Pathway

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G蛋白偶联受体

Endothelium-leukocyte interaction is critical for inflammatory responses. Whereas the tissue microenvironments are often acidic at inflammatory sites, the mechanisms by which cells respond to acidosis

Figshare2016-01-18 更新50

Data_Sheet_1_Suppressor of Cytokine Signaling 3 (SOCS3) Degrades p65 and Regulate HIV-1 Replication.PDF

HIV-1复制调控

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Human Immunodeficiency Virus-1 (HIV-1) is known to induce the expression of SOCS3 which is a negative feed-back regulator of inflammatory responses. Here, we demonstrate that reactivation of latent HI

NIAID Data Ecosystem40

NAIL: an evolutionarily conserved lncRNA essential for coordinating p38 activation and NFκB mediated chromatin remodelling in inflammation_3. NAIL: an evolutionarily conserved lncRNA essential for coordinating p38 activation and NFκB mediated chromatin remodelling in inflammation_3

炎症信号通路

非编码RNA功能

We report the differential gene expression analysis in MCF7-NAILWT and MCF7-NAILΔNFκB cells stimulated with TNF alpha for 0min, 45min and 90 min. Overall design: MCF7-NAILWT and MCF7-NAILΔNFκB cells (

NIAID Data Ecosystem60

JNK1 Signaling Downstream of the EGFR Pathway Contributes to Imiquimod-induced Skin Inflammation (RNA-seq)

银屑病分子机制

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c-Jun N-terminal protein kinase 1 (JNK1) is involved in multiple biological processes but its implication in inflammatory skin diseases is still poorly defined. Herein, we studied the role of JNK1 in

NIAID Data Ecosystem50

Double-stranded RNA induces molecular and inflammatory signatures that are directly relevant to COPD

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