Potential off-target effects were assessed using a stringent prediction criterion: off-target sites with a score <1.5 for canonical protospacer adjacent motif (5’-NGG-3’) or <2.0 for non-canonical pro
Exome sequencing on two independent models of myeloid neoplasms was performed to query off-target effects of Cas9 nuclease. Aligned sequencing data was filtered for reads overlapping predicted off-tar
Exome sequencing on two independent models of myeloid neoplasms was performed to query off-target effects of Cas9 nuclease. Aligned sequencing data was filtered for reads overlapping predicted off-tar
Exome sequencing on two independent models of myeloid neoplasms was performed to query off-target effects of Cas9 nuclease. Aligned sequencing data was filtered for reads overlapping predicted off-tar
