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Off-target analysis of CRISPR genome editing
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创建时间：
2021-03-30
相关数据集
k-mer analysis of genome-edited potatoes. Solanum tuberosum strain:Sassy
Genome editing technology is a powerful tool in breeding. In order to commercialize genome-edited crops, it is very important to confirm that no foreign genes remain in the genome. The goal of this st
NIAID Data Ecosystem80
Seven CRISPR-Cas9 benchmark off-target datasets used in our study.
Six of them include gRNA-target pairs with mismatches only, and one of them (CIRCLE, denoted with an asterisk) includes gRNA-target pairs with both mismatches and indels. Minority class samples corres
NIAID Data Ecosystem10
SpCas9 bound to FANCF off-target3 DNA substrate
SpCas9 bound to FANCF off-target3 DNA substrate
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Deep sequencing of top 24 off-target sites identified by iGUIDE (wrongly submitted)
We successfully develop a two-in-one approach to generate non-viral genome specific targeted CAR T cells through CRISPRCas9. In the adoptive therapy for relapsedrefractory aggressive B-cell non-Hodgki
NIAID Data Ecosystem50
On- and off-target effects of paired CRISPR-Cas nickase in primary human cells - long read. On- and off-target effects of paired CRISPR-Cas nickase in primary human cells - long read
Undesired on- and off-target effects of CRISPR-Cas nucleases remain a challenge in therapeutic genome editing. While the use of Cas9 nickases has been shown to minimize off-target mutagenesis, their u
NIAID Data Ecosystem10
