Multicyclic peptide molecules targeting TROP2 with high affinity

NIAID Data Ecosystem2026-05-02 收录

肿瘤靶向治疗

多环肽药物设计

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https://www.rcsb.org/structure/8WGJ 数据链接链接失效反馈

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Multicyclic peptide molecules targeting TROP2 with high affinity

创建时间：

2025-04-23

SAM Competitive PRMT5 Inhibitor PF-06939999 Demonstrates Antitumor Activity in Splicing Dysregulated NSCLC with Decreased Liability of Drug Resistance

肿瘤靶向治疗

药物耐药机制

Protein arginine methyltransferase 5 (PRMT5) over-expression in hematological and solid tumors methylates arginine residues on cellular proteins involved in important cancer functions including cell c

NIAID Data Ecosystem90

Subsequent treatments after progression on CDK 4/6 inhibitors.

肿瘤靶向治疗

乳腺癌耐药管理

Subsequent treatments after progression on CDK 4/6 inhibitors.

NIAID Data Ecosystem70

Table_1_Fusion Genes Altered in Adult Malignant Gliomas.DOC

恶性胶质瘤融合基因

肿瘤靶向治疗

Malignant gliomas are highly heterogeneous brain tumors in molecular genetic background. Despite the many recent advances in the understanding of this disease, patients with adult high-grade gliomas r

NIAID Data Ecosystem40

肿瘤靶分子临床研究信息数据集

肿瘤靶向治疗

临床研究

聚焦肿瘤靶分子临床研究全流程，整合靶点发现、临床试验设计、疗效数据、安全性评估等核心信息。数据经标准化清洗与专业校验，关联靶点分子结构、作用机制及临床结果，支持科研机构靶点验证、药企药物研发、临床机构方案优化，为靶分子临床转化提供高质量、可溯源的数据支撑。

江苏数据交易所80

Successful BRAF/MEK-inhibition in a young patient with BRAF V600E-mutated extrapancreatic acinar cell carcinoma (HIPO-021)

肿瘤靶向治疗

癌症基因组分析

Pancreatic acinar cell carcinoma (PAC) is a rare but dismal disease with a peak incidence rate around 60 to 70 years of age. Treatment options in case of metastatic disease are limited and often follo

NIAID Data Ecosystem50

Multicyclic peptide molecules targeting TROP2 with high affinity

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