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The effect of ADAR1 depletion on mitochondrial proteins

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NIAID Data Ecosystem2026-05-10 收录
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https://www.omicsdi.org/dataset/pride/PXD069896
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In this study, we found that ADAR1 reduces the levels of double-stranded RNAs (dsRNAs) derived from both nuclear and mitochondrial transcripts. To elucidate how ADAR1 controls mitochondrial dsRNA (mt-dsRNA) accumulation, we performed quantitative mass spectrometry on mitochondrial protein fractions from wild-type and ADAR1-deficient cells, aiming to identify mitochondrial protein mediators involved in ADAR1-dependent dsRNA regulation.
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2026-01-23
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