首页/数据集/Crystal structures of mutant Dpo4 DNA polymerases with 8-oxoG containing DNA template-primer constructs

Crystal structures of mutant Dpo4 DNA polymerases with 8-oxoG containing DNA template-primer constructs

NIAID Data Ecosystem2026-05-01 收录

DNA损伤修复

聚合酶结构生物学

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https://www.rcsb.org/structure/2UVU 数据链接链接失效反馈

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资源简介：

Crystal structures of mutant Dpo4 DNA polymerases with 8-oxoG containing DNA template-primer constructs

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创建时间：

2023-12-13

DNA损伤修复

抗癌药物设计

Homologous recombination repair (HRR), a crucial approach in DNA damage repair, is an attractive target in cancer therapy and drug design. The Bloom syndrome protein (BLM) is a 3′–5′ DNA helicase that

NIAID Data Ecosystem40

p38-MK2 regulate RNA metabolism after UV light-induced DNA damage

DNA损伤修复

转录调控

Ultraviolet (UV) light induces the formation of bulky UV photoproducts in the genome that interfere with DNA replication and transcription. It is well-established how human cells repair UV light-induc

NIAID Data Ecosystem20

Transcriptome analysis of IR-treated HL-60 cells (shCtrl and shPTIP)

DNA损伤修复

基因表达调控

To explore the underlying molecular mechanisms behind DNA damage repair, gene expression profiles of shCtrl- and shPTIP (#1 and #2)-transduced HL-60 cells at 0 min and 180 min after IR were examined b

NIAID Data Ecosystem10

Aminofluorene DNA adduct at the pre-insertion site of a DNA polymerase

DNA损伤修复

跨损伤合成

Aminofluorene DNA adduct at the pre-insertion site of a DNA polymerase Descriptor: 2-AMINOFLUORENE, DNA polymerase I, DNA primer strand, ... Authors: Hsu, G.W, Kiefer, J.R, Becherel, O.J, Fuchs, R.P.P

Protein Data Bank Japan2023-08-23 更新30

C. thermocellum UvrA in complex with DNA with a fluorescein modification and ADP (basal conformation)

DNA损伤修复

DNA复合物

C. thermocellum UvrA in complex with DNA with a fluorescein modification and ADP (basal conformation)

NIAID Data Ecosystem10