NEDD4L mediates intestinal epithelial cell ferroptosis to restrict inflammatory bowel diseases [colonic tissues without isolation]

To explore the underlying mechanisms of NEDD4L in regulating colitis, colonic tissues from DSS-treated Nedd4lf/f VillinCre (IEC KO) mice and Nedd4lf/f (WT) littermates were subjected to RNA-sequencing analysis. Gene expression profiling analysis of RNA-seq data from colonic tissues on the 7th day from the Nedd4lf/fVillinCre and Nedd4lf/f mice administered 2 % DSS .