Characteristics of in silico predicted L. major specific CD8+ T cell 9-mer peptides included in the polytope construct.

* Peptides analyzed in HLA transgenic mice (P1–P6) and BALB/c mice (Kd1–Kd4) are in bold.aModerate binder.bHigh binder.#Peptide falling over pre-set threshold.(1) http://www.syfpeithi.de/bin/MHCServer.dll/EpitopePrediction.htm.(2) http://www-bimas.cit.nih.gov/molbio/hla_bind/.(3) http://www.jenner.ac.uk/EpiJen/.(4) http://immunax.dfci.harvard.edu/Tools/rankpep.html.(5) http://www.imtech.res.in/raghava/nhlapred/comp.html.(6) http://www.cbs.dtu.dk/services/NetCTL/.(7) http://antigen.i2r.a-star.edu.sg/multipred.CPB (Cathepsin L-like Protease or Type I Cysteine Proteinase), CPC (Cathepsin L-like Protease or Type I Cysteine Proteinase), LmsTI-1 (L.major Stress Indussible Protein), LPG-3 (Lipophosphoglycan Biosynthetic Protein).Characteristics of in silico predicted L. major specific CD8+ T cell 9-mer peptides included in the polytope construct.