Gene ontology enrichment analysis of the top 200 genes.

Out of 1732 genes/proteins, the 200 genes/proteins with the highest weight (estimated using POPLS-DA) were used to perform GO enrichment analysis. All three GO ontologies were considered: cellular compound (CC), biological process (BP), and molecular function (MF). For each term, a p-value was computed using Fisher’s exact test with the whole genome as background and corrected for multiple testing. The ten most significant terms are shown, ranked by their GO enrichment false discovery rate (FDR) adjusted p-value. The column “Genes in set” shows how many of the top 200 genes/proteins were annotated with the respective term.