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Metabolic targeting as a strategy to overcome targeted therapy resistance in NRAS-mutated melanoma. Metabolic targeting as a strategy to overcome targeted therapy resistance in NRAS-mutated melanoma

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NIAID Data Ecosystem2026-03-14 收录
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We used single cell RNA sequencing (scRNA-seq) to analyze the molecular response of melanoma xenografts to combined MEK-inhibitng and metabolic targeting therapy. Overall design: Patient-derived melanoma cell cultures were injected into the flank of Balb-c/nude mice. The xenografts of the different treatment groups were analyzed using scRNAseq.

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2023-01-05
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