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Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a fragment

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Protein Data Bank Japan2023-09-27 更新2026-03-21 收录
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https://pdbj.org/mine/summary/5ctx
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Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a fragment Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-phenyl-3-[2-(pyridin-3-yl)-1,3-thiazol-5-yl]-2,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one, DNA gyrase subunit B, ... Authors: Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C, Mesleh, M, Cross, J.B, Zhang, J, Yang, Q, Lippa, B, Ryan, M.D. Deposit date: 2015-07-24 Release date: 2016-02-03 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB. Bioorg.Med.Chem.Lett., 26, 2016
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2015-07-24
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