Deafness Variation Database

耳聋基因变异数据库（Deafness Variation Database, DVD）是一个关于听力损失相关基因变异的公共专家策展资源。该数据库由爱荷华大学分子耳鼻喉与肾脏研究实验室于2011年建立和维护，旨在通过严格整理、注释、分类和公开共享证据，推进对耳聋相关基因变异的准确分类，以支持临床诊断和决策。The Deafness Variation Database (DVD) is a public expert-curated resource focused on genetic variants associated with hearing loss. Established and maintained in 2011 by the Molecular Otolaryngology and Renal Research Laboratories at the University of Iowa, this database aims to advance the accurate classification of deafness-associated genetic variants through rigorous curation, annotation, classification, and public sharing of supporting evidence, in order to support clinical diagnosis and decision-making.

搜集汇总

背景与挑战

背景概述

Deafness Variation Database（DVD）是一个由爱荷华大学分子耳鼻喉与肾脏研究实验室于2011年建立的公共专家策展资源，专注于听力损失相关基因变异。它通过严格整理、注释和分类证据，旨在推进耳聋基因变异的准确分类，以支持临床诊断和决策，当前版本涵盖224个耳聋相关基因。