Overview of primary time (hours), RMC (%), and BCG survival rate (%) as a function of the freeze-drying cycle and freeze-dryer scale.
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Several methods were used for primary drying endpoint determination: the vacuum valve open/close frequency, the outlet condenser temperature, and PRT refers to the pressure rise test. The maximum load of the freeze-dryers is as follows: 12500 vials at production scale and 750 vials at pilot scale. See S1 Data for raw data.
创建时间：
2016-09-29
