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Description of simulation scenarios.

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aIn each scenario (apart from 5c and 5d) the baseline regression coefficient was chosen to equal (0.02/0.98), corresponding to a baseline penetrance of 2%. bFor Scenarios 6–9 we increased from 0 (no interaction) to a value at which the power to detect an effect (at significance level 0.01) was close to 100% for the best-performing statistics.

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2012-04-05
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