Data From NaF PROSTATE

This is a collection of F-18 NaF positron emission tomography/computed tomography (PET/CT) images in patients with prostate cancer, with suspected or known bone involvement. Imaging was performed on a Phillips Gemini TF PET/CT scanner based on 4x4x22mm LYSO (lutetium yttrium orthosilicate) crystal detection elements covering 18cm axial field of view (FOV) and 57cm imaging transaxial FOV. The time of flight resolution is 585ps. The scanner achieves a spatial resolution of 4.8mm at the center of the FOV. Data were reconstructed using the RAMLA iterative OSEM algorithm using 3 iterations and 33 subsets. The scanner uses CT based attenuation correction, along with randoms, normalization, dead time, and a model based scatter correction. The CT component of the scanner is a 16 slice helical CT. The CT images were generated using a low X-ray dose of 120KV, 60mAs setting. The prescribed injected dose was 3mCi IV. Some of the patients had 2 baseline studies within 14 days of each other (with no intervening interventions). Many have follow-up PET/CT imaging performed following therapy (varied) at 6 +/-2months and 12 +/- 2 months.

本数据集收录了前列腺癌疑似或确诊骨受累患者的氟-18氟化钠（F-18 NaF）正电子发射断层显像/计算机断层扫描（positron emission tomography/computed tomography, PET/CT）图像。成像采用基于4×4×22mm硅酸镥钇（lutetium yttrium orthosilicate, LYSO）晶体探测单元的飞利浦（Phillips）Gemini TF PET/CT扫描仪，该设备轴向视野（axial field of view, FOV）覆盖18cm，横向成像视野为57cm，飞行时间分辨率达585皮秒（ps），视野中心空间分辨率为4.8mm。数据采用RAMLA迭代有序子集期望最大化（OSEM）算法进行重建，迭代次数为3次，子集数为33个。该扫描仪采用基于CT的衰减校正方法，辅以随机符合校正、归一化校正、死时间校正以及基于模型的散射校正。扫描仪的CT成分为16层螺旋CT，CT图像采用120KV、60mAs的低剂量X射线参数采集。规定注射剂量为3毫居（mCi）静脉给药。部分患者在14天内完成2次基线检查（期间无干预措施）；多数患者在接受个体化治疗后，分别于治疗后6±2个月及12±2个月完成随访PET/CT成像。