Gene expression profile at single cell level of tumor infiltrating myeloid antigen presenting cells from tonsillar cancer patients. Gene expression profile at single cell level of tumor infiltrating myeloid antigen presenting cells from tonsillar cancer patients

Myeloid antigen presenting cells are a heterogeneous population, and their identity is greatly influenced by niche specific cues. We used single cell RNA sequencing (scRNA-seq) to analyze the diversity of myeloid antigen presenting cells in tonsillar cancer tissue and paired contralateral healthy tissue. Overall design: Myeloid antigen presenting cells from tonsillar cancer patients were isolated by Fluorescence-activated cell sorting (FACS) according to the presence of CD13 and HLA-DR and analyzed using scRNAseq.