Amino acid variation in Gag p17 and p24 associated with HLA-B^*57/58:01 disease progression.

*The Sequence Harmony (SH) score represents overlap in amino acid composition between the two groups analyzed (HLA-B*57/58:01 progressors versus HLA-B*57/58:01 LTNPs). An SH value of 0 indicates no overlap (largest possible differences) while a value of 1 indicates complete overlap (no differences). **All Z scores represent P values <0.0001 with correction for multiple testing (450 alignment positions). ***The most frequent amino acids found at a certain position are depicted as “Dominant”, whereas the “Minor” amino acids are present at least 2 times less frequent than the most frequently occurring amino acid at this position. Amino acids are ordered from highest to lowest frequency.