Hazard ratios (HR) for all-cause mortality and CVD-related mortality by serum leptin quartile.

a Tests for linear trend used leptin as a continuous variable in logistic regression.b Model 1: Adjusted for age, race, site, years of education, alcohol use, smoking, and physical activity (total calorie intake, HRT use among women and numbers of hours fasted were not significant and did not affect the association between predictor and outcome, so they were not included in the model)c Model 2: Adjusted for variables in model 1 plus TOTPF, CRP, PAI-1, TNF, and IL6Hazard ratios (HR) for all-cause mortality and CVD-related mortality by serum leptin quartile.