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Complex of Aldose Reductase with NADP+ and simaltaneously bound competetive inhibitors Fidarestat and IDD594. Concentration of Fidarestat in soaking solution is less than concentration of IDD594.

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Protein Data Bank Japan2023-08-30 更新2026-03-21 收录
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Complex of Aldose Reductase with NADP+ and simaltaneously bound competetive inhibitors Fidarestat and IDD594. Concentration of Fidarestat in soaking solution is less than concentration of IDD594. Descriptor: (2S,4S)-2-AMINOFORMYL-6-FLUORO-SPIRO[CHROMAN-4,4'-IMIDAZOLIDINE]-2',5'-DIONE, Aldose reductase, CHLORIDE ION, ... Authors: Petrova, T, Hazemann, I, Cousido, A, Mitschler, A, Ginell, S, Joachimiak, A, Podjarny, A. Deposit date: 2007-04-05 Release date: 2007-04-17 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (0.85 Å) Cite: Crystal packing modifies ligand binding affinity: The case of aldose reductase. Proteins, 80, 2012
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2007-04-05
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