Mdivi-1 treatment regulates embryo epigenome. Mdivi-1 treatment regulates embryo epigenome

NIAID Data Ecosystem2026-03-14 收录

胚胎表观遗传学

发育生物学干预

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA916668 数据链接链接失效反馈

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We mouse early embryos with Mdivi-1 and exmained changes of embryo epigenome. Overall design: We treated mouse early embryos with Mdivi-1 and identified changes of 2-cell embryo epigenome.

创建时间：

2022-12-29

Single Cell DNA Methylome Sequencing of Human Preimplantation Embryos

胚胎表观遗传学

单细胞甲基化

Although the DNA methylome of human early embryos has been analyzed, some of the key features have not been addressed to date. Here, we performed single-cell DNA methylome sequencing for human preimpl

NIAID Data Ecosystem100

Rlf, a widely-spaced zinc finger protein, is involved in maintaining epigenetic marks at CpG island shores and enhancer elements across the genome

甲基化调控基因

胚胎表观遗传学

We recently identified a novel protein, Rearranged L-myc fusion (Rlf), that is required for DNA hypomethylation (and transcriptional activity) at certain regions of the mouse genome known to be sensit

NIAID Data Ecosystem50

Genome-wide histone modification profiling of inner cell mass and trophoectoderm of blastocyst stage bovine embryos by novel low input RAT-ChIP. Genome-wide histone modification profiling of inner cell mass and trophoectoderm of blastocyst stage bovine embryos by novel low input RAT-ChIP

胚胎表观遗传学

组蛋白修饰谱分析

Chromatin immunoprecipitation coupled with next-generation sequencing (ChIP-seq) has revolutionized our understanding of chromatin related biological processes. The method, however, requires thousands

NIAID Data Ecosystem30

Table1_Whole-Genome DNA Methylation Dynamics of Sheep Preimplantation Embryo Investigated by Single-Cell DNA Methylome Sequencing.XLS

胚胎表观遗传学

单细胞甲基化

The early stages of mammalian embryonic development involve the participation and cooperation of numerous complex processes, including nutritional, genetic, and epigenetic mechanisms. However, in embr

NIAID Data Ecosystem60

Genome-Wide DNA Methylation Patterns of Bovine Blastocysts Developed In Vivo from Embryos Completed Different Stages of Development In Vitro

胚胎表观遗传学

体外胚胎培养评估

Early embryonic loss and altered gene expression in in vitro produced blastocysts are believed to be partly caused by aberrant DNA methylation. However, specific embryonic stage which is sensitive to

NIAID Data Ecosystem40

Mdivi-1 treatment regulates embryo epigenome. Mdivi-1 treatment regulates embryo epigenome

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