Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and L3mbtl2 cKO Testicular Transcriptomes. Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and L3mbtl2 cKO Testicular Transcriptomes

Our study represents the first detailed analysis of testicular transcriptomes, with biologic replicates, generated by RNA-seq technology. The optimized data analysis workflows reported here should provide a framework for comparative investigations of expression profiles. Overall design: Testicular mRNA profiles of 8-month-old contol and L3mbtl2 cKO mice were generated by deep sequencing, in triplicate, using Illumina HiSeq platform.