Performance of the models.

χ2 = Chi-Square. P values vs Model 1 (Clinical). AIC = Akaike information criterion; BIC = Bayesian information criterion; HL = Hosmer–Lemeshow test; hs-cTnT, = high-sensitivity circulating troponin T; ST2 = high-sensitivity soluble ST2; IDI = integrated discrimination improvement; NRI = net reclassification improvement. NT-proBNP = N-terminal pro-brain natriuretic peptide. Model 1 (Clinical) = Age, Female, NYHA functional class (as I−II vs III−IV), LVEF (as ≥ vs <45%), eGFR (estimated glomerular filtration rate), Sodium, Hemoglobin, Furosemide-equivalent doses treatment as 0, ≤40 mg/day and >40 mg/day or Torasemide as 0, ≤10 mg/day and >10 mg/day), ACEI or ARB treatment, beta-blocker treatment, statin treatment. Model 2 = Model 1+NT-proBNP. Model 3 = Model 1+hs-cTnT. Model 4 = Model 1+ST2. Model 5 = Model 1+NT-proBNP+ST2. Model 6 = Model 1+NT-proBNP+hs-cTnT. Model 7 = Model 1+hs-cTNT+ST2. Model 8 = Model 1+NT-proBNP+hs-cTNT.