Whole genome microRNA expression profiling during C. elegans dietary restriction
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https://www.ncbi.nlm.nih.gov/sra/SRP045301
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In order to get an insight into the complex interplay of miRNAs in dietary restriction, we profiled the small RNA polulation of wild-type and eat-2(ad1116) worms on Day 1 and Day 8 of adulthood by Next Generation sequencing. We compared the normalized expression of wild-type vs eat-2(ad1116) on either day 1 or day 8 and found that most of the miRNAs were distinctly upregulated in eat-2(ad1116) on day 1. Overall design: We performed Next Generation sequencing to compare miRNA profiles of wild-type and eat-2(ad1116) at Day 1 and Day 8
创建时间:
2017-09-17



