Crystal structure of the Keap1 Kelch domain in complex with the XChem fragment Z19735904 at 1.14 Angstrom resolution.

Crystal structure of the Keap1 Kelch domain in complex with the XChem fragment Z19735904 at 1.14 Angstrom resolution. Descriptor: DIMETHYL SULFOXIDE, Kelch-like ECH-associated protein 1, SULFATE ION, ... Authors: Narayanan, D, Bach, A, Gajhede, M. Deposit date: 2025-01-06 Release date: 2025-09-03 Last modified: 2025-10-08 Method: X-RAY DIFFRACTION (1.14 Å) Cite: Fragment-Based Drug Discovery of Novel High-affinity, Selective, and Anti-inflammatory Inhibitors of the Keap1-Nrf2 Protein-Protein Interaction. Angew.Chem.Int.Ed.Engl., 64, 2025