Gene expression profiles in GC B cells during acute and chronic viral infection
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https://www.ncbi.nlm.nih.gov/sra/SRP298209
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To study how chronic viral infection disrupts B cell differentiation pathways and identify key intrinsic regulators in an endogenous polyclonal response, we used the comparative LCMV model. Wild-type mice were infected with either the acute (WE) versus chronic (Docile) strains of LCMV, GC B cells (CD19+IgDloCD95+CD38loCD138-) isolated 14 days post-infection, and RNA-seq was undertaken Overall design: 4 samples . Each group has at least 2 biological replicates.
创建时间:
2022-01-20



