This data record is comprised of 46 data sets of epistatic effects on 23 quantitative traits of LOAD patients from ADNI cohort. These 46 data sets are available for download in a form of combined data
Genetic effects are often context-dependent, with the same genotype differentially affecting phenotypes across environments, life stages, and sexes. We used an environmental manipulation designed to i
This file contains digenic and trigenic interaction scores at an established interaction magnitude cut-off for digenic interactions (p 0.08) and trigenic interactions (p < 0.05, < -0.08)
Hydrolases are a critical component for modern chemical, pharmaceutical, and environmental sciences. Identifying mutations that enhance catalytic efficiency presents a roadblock to design and to disco