Tractography Templates for White Matter Microstructure Analysis in Aging and Alzheimer's Disease

This dataset contains tractography templates derived from several studies focused on white matter microstructure and its associations with neurodegenerative diseases, particularly Alzheimer's disease and Parkinsonism. These templates span key tracts relevant to both cognitive decline and motor function, including but not limited to the medial temporal lobe white matter, transcallosal fibers, sensorimotor tracts, and the fornix. The templates were developed and validated using advanced diffusion MRI techniques across various populations, including aging individuals, dementia patients, and those at risk of neurodegenerative conditions. This resource serves as a valuable tool for researchers investigating the structural integrity of white matter in both health and disease, allowing for cross-study comparability and enhancing the understanding of neurodegenerative processes.