Variability in functional p53 reactivation by Prima-1Met/APR-246 in Ewing sarcoma

ChEBI2013-11-12 更新2026-07-21 收录

肿瘤靶向治疗

p53通路

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-49967 数据链接链接失效反馈

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资源简介：

Variability in functional p53 reactivation by Prima-1Met/APR-246 in Ewing sarcoma

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2013-11-12

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肿瘤靶向治疗

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TP53 mutations are highly associated with hepatocellular carcinoma (HCC), a common and deadly cancer. However, few primary drivers in the progression of HCC with mutant TP53 have been identified. To u

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肿瘤靶分子临床研究信息数据集

肿瘤靶向治疗

临床研究

聚焦肿瘤靶分子临床研究全流程，整合靶点发现、临床试验设计、疗效数据、安全性评估等核心信息。数据经标准化清洗与专业校验，关联靶点分子结构、作用机制及临床结果，支持科研机构靶点验证、药企药物研发、临床机构方案优化，为靶分子临床转化提供高质量、可溯源的数据支撑。

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Ganglioside GD2 identifies Breast Cancer Stem Cells: Targeting GD3 Synthase Inhibits GD2 Expression and Tumor Growth. Homo sapiens

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We FACS sorted Ras-transformed human mammary epithelial cells (HMLER cells) into GD2+ and GD2- as well as CD44high/CD24low and CD44low/Cd24highcells and comapred the four different population by array

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Variability in functional p53 reactivation by Prima-1Met/APR-246 in Ewing sarcoma

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